Effect of Altitude Acclimatization on Lung NO and CO Concentration and Vascular Tone in Humans
(Drs. Bar-Yosef, Piantadosi, Moon). A joint study with members from the Department of Medicine examining the hypothesis that PO2-related changes in pulmonary and systemic vascular resistance in humans are mediated by changes in pulmonary NO and CO content. Analysis is in progress of data obtained from a prolonged exposure to 15,000 ft altitude in which volunteers are instrumented with arterial and pulmonary artery catheters.